Table 4. Effects of the pain stimulation across the groups (second level analysis).
| Placebo group (n = 25) | Oxytocin group (n = 23) | Conditioned group (n = 25) | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Cluster size | T max | X (mm) | Y (mm) | Z (mm) | Cluster size | T max | X (mm) | Y (mm) | Z (mm) | Cluster size | T max | X (mm) | Y (mm) | Z (mm) | |
| pain>control | |||||||||||||||
| WB right postcentral gyrus with extension to precentral gyrus | 10776 | 6.82 | 48 | -26 | 64 | 455 | 6.36 | 48 | -20 | 58 | 21 | 4.81 | 60 | -4 | 28 |
| WB left temporal occipital fusiform cortex | 1786 | 5.23 | -28 | -38 | -24 | ||||||||||
| WB left temporal occipital fusiform cortex with extension to left occipital fusiform gyrus | 27763 | 8.18 | -26 | -46 | -10 | ||||||||||
| WB right parahippocampal gyrus with extension to temporal fusiform cortex | 623 | 6.77 | 26 | -24 | -24 | 32709 | 7.79 | 22 | -22 | -18 | |||||
| WB bilateral occipital pole | 248 | 5.19 | 0 | -88 | 40 | ||||||||||
| WB right lateral occipital cortex | 217 | 4.89 | 44 | -68 | 26 | ||||||||||
| WB bilateral precuneous cortex | 162 | 4.15 | 10 | -60 | 14 | ||||||||||
| WB left thalamus | 118 | 4.8 | -14 | -32 | 10 | ||||||||||
| WB left middle temporal gyrus | 87 | 4.35 | -68 | -8 | -10 | 25 | 4.01 | -52 | -12 | -18 | |||||
| WB brain stem | 81 | 4.68 | -2 | -26 | -22 | ||||||||||
| WB angular gyrus | 33 | 3.45 | 48 | -54 | 30 | ||||||||||
| WB right cingulate gyrus | 21 | 3.57 | 8 | -50 | 6 | ||||||||||
| WB bilateral cuneal cortex | 15 | 3.26 | -2 | -84 | 36 | ||||||||||
| WB frontal pole with extension to right paracingulate gyrus | 1212 | 5.54 | 0 | 66 | 4 | ||||||||||
| WB left superior frontal gyrus | 278 | 5.12 | -24 | 22 | 42 | ||||||||||
| ROI left amygdala | 78 | 4.53 | -20 | -10 | -24 | 18 | 5.03 | -20 | -16 | -18 | |||||
| 26 | 4.37 | -26 | -2 | -32 | |||||||||||
| ROI right amygdala | 38 | 4.55 | 14 | -4 | -24 | 173 | 4.17 | 24 | 2 | -26 | |||||
| pain < control | |||||||||||||||
| WB right precentral gyrus | 837 | 6.52 | 46 | 10 | 26 | ||||||||||
| WB left precentral gyrus | 23 | 5.55 | -58 | 6 | 4 | ||||||||||
| WB right frontal operculum cortex to insula and central opercular cortex | 1484 | 11 | 48 | 18 | 0 | ||||||||||
| WB right central opercular cortex | 121 | 5.79 | 52 | 0 | 8 | ||||||||||
| WB right frontal pole | 68 | 5.53 | 40 | 38 | 8 | ||||||||||
| WB right insular cortex | 422 | 6.95 | 34 | 12 | 10 | ||||||||||
WB- results obtained with the whole brain analysis; ROI- results obtained with the region of interest analysis. Reported activations are corrected for multiple comparisons with the threshold-free cluster enhancement. Coordinates are reported using the Montreal Neurologic Institute space.