Table 4. Hazard ratios for ApaI +64978C>A genotypes by severity at first MDE.

	Severity
ApaI	Mild and Moderate	Severe
A/A	0.469 (p = 0.239; 95% CI = 0.133–1.656) *	3.018 (p = 0.105, 95% CI = 0.794–14.468) *
C/A	0.289 (p = 0.033, 95% CI = 0.092–0.908) *	3.265 (p = 0.041, 95% CI = 1.047–10.182) *
C/C	1	1

*Hazard ratio, controlling for age at first MDE