Table 2. Summary of studies on the recent advances in the biochemistry of PPGLs.
Authors | Journal | Year | Findings |
---|---|---|---|
Weismann et al. (56) | European Journal of Endocrinology | 2015 | Higher sensitivity and specificity of plasma metanephrines measurement using LC-MS/MS |
Rao et al. (57) | European Journal of Endocrinology | 2017 | Measurement of plasma methoxytyramine enables the detection of PPGLs which exclusively secrete dopamine |
Inclusion of methoxytyramine to the standard biochemical test panel yields better diagnostic utility | |||
Eisenhofer et al. (58) | Clinical Chemistry | 2018 | Plasma free metabolite is a better diagnostic test for PPGLs than urinary fractionated metabolites with a higher sensitivity and specificity |
PPGL, pheochromocytomas and paragangliomas.