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. 2020 Feb;9(1):105–123. doi: 10.21037/gs.2019.10.25

Table 2. Summary of studies on the recent advances in the biochemistry of PPGLs.

Authors Journal Year Findings
Weismann et al. (56) European Journal of Endocrinology 2015 Higher sensitivity and specificity of plasma metanephrines measurement using LC-MS/MS
Rao et al. (57) European Journal of Endocrinology 2017 Measurement of plasma methoxytyramine enables the detection of PPGLs which exclusively secrete dopamine
Inclusion of methoxytyramine to the standard biochemical test panel yields better diagnostic utility
Eisenhofer et al. (58) Clinical Chemistry 2018 Plasma free metabolite is a better diagnostic test for PPGLs than urinary fractionated metabolites with a higher sensitivity and specificity

PPGL, pheochromocytomas and paragangliomas.