Table 3.

Distribution of Medication Use in 2007 and 2014 among Antidepressant Users According to Duration of Use and Regimen (Concomitant Use or Monotherapy).

	2007		2014
	N	%	N	%
Total AD Users	9,589	100	14,777	100
Duration < 30 days	922	9.62	868	5.87
Duration ≥ 30 days	8,667	90.38	13,909	94.13
AD + ≥3 classes	665	6.95	1,075	7.27
AD + 2 classes	1,857	19.37	2,643	17.89
AD + 1 class	3,129	32.63	4,352	29.45
AD monotherapy	3,016	31.45	5,839	39.51
Duration < 60 days	3,401	35.47	4,573	30.94
Duration ≥ 60 days	6,188	64.53	10,204	69.06
AD + ≥3 classes	499	5.20	827	5.60
AD + 2 classes	1,400	14.60	2,104	14.24
AD + 1 classes	2,360	24.61	3,282	22.21
AD monotherapy	1,929	20.12	3,991	27.01

Regardless of duration of use (30 days or 60 days) or year (2007 or 2014), the top combinations were –

Combination of 4 or more:

Antidepressant + Alpha agonists + Antipsychotics + Stimulants

Antidepressant + Alpha agonists + Antipsychotics + Stimulants + Mood stabilizers

Antidepressant + Stimulants + Antipsychotics + Atomoxetine

Antidepressant + Alpha agonists + Antipsychotics + Mood stabilizers

Combination of 3:

Antidepressant + Antipsychotics + Stimulants

Antidepressant + Alpha agonists + Stimulants

Antidepressant + Stimulants + Mood stabilizers

Antidepressant + Alpha agonists + Antipsychotics

Combination of 2:

Antidepressant + Stimulants

Antidepressant + Antipsychotics

Antidepressant + Mood stabilizers

Antidepressant + Hypnotics

Antidepressant + Alpha agonists