Skip to main content
. 2020 Mar 13;11:314. doi: 10.3389/fphar.2020.00314

Table 4.

Generalised estimating equation (GEE) model analysis of haematological parameters [Basophils, Eosinophils, Lymphocytes, Monocytes, Neutrophils, and white blood cell (WBC)]: between and within group comparison.

Parameter
(x108/liter)		 Comparison Hour Difference 95% CI Probability
Lower Limit Upper Limit
Basophils Blacks vs Nonblacks 8 −0.07 −0.12 −0.02 0.0038
9 −0.05 −0.07 −0.03 <0.0001
10 −0.06 −0.08 −0.04 <0.0001
11 −0.06 −0.08 −0.03 <0.0001
12 −0.07 −0.09 −0.05 <0.0001
13 −0.04 −0.06 −0.02 0.0009
14 −0.07 −0.08 −0.05 <0.0001
15 −0.07 −0.08 −0.05 <0.0001
16 −0.05 −0.07 −0.03 <0.0001
17 −0.05 −0.07 −0.03 <0.0001
18 −0.04 −0.08 −0.01 0.0127
All time points −0.06 −0.07 −0.04 <0.0001
Morning vs Evening Blacks −0.02 −0.04 0.01 0.1352
Nonblacks −0.01 −0.01 0.00 0.2083
All −0.01 −0.02 0.00 0.0611
Eosinophils Blacks vs Nonblacks 8 −0.44 −1.17 0.30 0.2430
9 −0.20 −0.42 0.02 0.0793
10 −0.19 −0.38 0.01 0.0584
11 0.11 −0.28 0.49 0.5957
12 −0.29 −0.51 −0.07 0.0110
13 −0.16 −0.37 0.05 0.1378
14 −0.04 −0.24 0.16 0.7168
15 −0.14 −0.31 0.03 0.1119
16 −0.10 −0.27 0.06 0.2220
17 0.05 −0.30 0.40 0.7815
18 −0.30 −0.55 −0.05 0.0176
All time points −0.15 −0.27 −0.04 0.0097
Morning vs Evening Blacks 0.09 −0.29 0.48 0.6289
Nonblacks 0.25 0.17 0.33 <0.0001
All 0.17 −0.02 0.36 0.0806
Lymphocytes Blacks vs Nonblacks 8 1.56 0.10 3.02 0.0367
9 0.85 −0.05 1.74 0.0629
10 0.04 −0.65 0.72 0.9207
11 1.18 0.38 1.98 0.0040
12 0.48 −0.20 1.15 0.1667
13 0.05 −0.58 0.69 0.8741
14 −0.01 −0.65 0.64 0.9809
15 0.29 −0.41 0.98 0.4203
16 0.06 −0.61 0.73 0.8576
17 0.60 −0.25 1.44 0.1658
18 0.80 −0.43 2.03 0.2021
All time points 0.53 0.14 0.93 0.0082
Morning vs Evening Blacks −2.17 −2.92 −1.41 <0.0001
Nonblacks −2.49 −2.82 −2.16 <0.0001
All −2.33 −2.74 −1.91 <0.0001
Monocytes Blacks vs Nonblacks 8 −0.85 −1.23 −0.46 <0.0001
9 −0.70 −1.00 −0.41 <0.0001
10 −0.91 −1.11 −0.70 <0.0001
11 −0.73 −0.95 −0.51 <0.0001
12 −0.74 −0.95 −0.54 <0.0001
13 −0.87 −1.06 −0.67 <0.0001
14 −0.92 −1.10 −0.75 <0.0001
15 −1.03 −1.22 −0.84 <0.0001
16 −0.98 −1.15 −0.81 <0.0001
17 −0.79 −1.06 −0.52 <0.0001
18 −0.97 −1.30 −0.65 <0.0001
All time points −0.86 −0.97 −0.75 <0.0001
Morning vs evening Blacks −0.30 −0.51 −0.08 0.0083
Nonblacks −0.39 −0.48 −0.30 <0.0001
All −0.34 −0.46 −0.22 <0.0001
Neutrophils (x109/liter) Blacks vs Nonblacks 8 −1.05 −1.37 −0.72 <0.0001
9 −1.07 −1.23 −0.91 <0.0001
10 −1.16 −1.32 −1.00 <0.0001
11 −1.13 −1.29 −0.97 <0.0001
12 −1.19 −1.35 −1.03 <0.0001
13 −1.16 −1.32 −0.99 <0.0001
14 −1.44 −1.62 −1.26 <0.0001
15 −1.46 −1.62 −1.29 <0.0001
16 −1.61 −1.76 −1.47 <0.0001
17 −1.52 −1.71 −1.34 <0.0001
18 −1.43 −1.69 −1.16 <0.0001
All time points −1.29 −1.38 −1.21 <0.0001
Morning vs evening Blacks −0.65 −0.80 −0.50 <0.0001
Nonblacks −1.08 −1.16 −0.99 <0.0001
All −0.86 −0.95 −0.78 <0.0001
White Blood Cells (x109/liter) Blacks vs Nonblacks 8 −1.05 −1.43 −0.67 <0.0001
9 −1.11 −1.30 −0.91 <0.0001
10 −1.29 −1.48 −1.10 <0.0001
11 −1.08 −1.29 −0.87 <0.0001
12 −1.26 −1.46 −1.07 <0.0001
13 −1.27 −1.46 −1.07 <0.0001
14 −1.52 −1.73 −1.32 <0.0001
15 −1.56 −1.76 −1.36 <0.0001
16 −1.73 −1.91 −1.55 <0.0001
17 −1.54 −1.76 −1.32 <0.0001
18 −1.48 −1.78 −1.17 <0.0001
All time points −1.35 −1.46 −1.25 <0.0001
Morning vs evening Blacks −0.91 −1.08 −0.73 <0.0001
Nonblacks −1.34 −1.43 −1.24 <0.0001
All −1.12 −1.22 −1.02 <0.0001