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Mean percentages of positivity of ICOS, CTLA-4, and PD-1 on CD4+ and CD8+ BM T cells.
| T cells | B7 ICR | AML | Healthy controls |
|---|---|---|---|
| CD4+ | ICOS | 56.9% | 57.5% |
| CTLA-4 | 3.6% | 1% | |
| PD-1 | 19.1% | 15.8 | |
| CD8+ | ICOS | 23.8% | 21.1% |
| CTLA-4 | 1.5% | 0.2% | |
| PD-1 | 27.7% | 27.2% |
AML, acute myeloid leukemia; BM, bone marrow; CTLA-4, cytotoxic T lymphocyte-associated protein 4; ICR, immune checkpoint receptor; PD-1, programmed death 1.
