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. 2020 Jan 2;14(4):881–895. doi: 10.1038/s41396-019-0580-z

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Heatmap representing select host genes’ fold change (log₂FC) expression in infected vs uninfected, separated into categories: a The operon (“op”) containing the genes nrdA, nrdB and ferredoxin is the highest expressed group in both virocells. b The operon containing 5 genes mainly involved in cellular transport that comprises the group of most under-expressed genes in both virocells. c An operon with putative membrane remodeling genes and the chaperones GroEL/ES is the highest expressed group in the HS2 virocells. d Underexpression of both flagellar synthesis and assembly and protein translation genes (including ribosomal RNA, ribosomal proteins and translation factors) in the HS2 virocells. e Overexpression of tRNA genes in the HP1 virocells, which are under-expressed in the HS2 virocells.