Table 5.
Comparison of the predictive scores’ association with short-term outcome
No. | AUC | Grade | Sens. (%) | Spec. (%) | PPV (%) | NPV (%) | pCut-off | |
---|---|---|---|---|---|---|---|---|
Death | ||||||||
Aronin Scale (%) | 101 | 0.53 | Failed | 33 | 83 | 11 | 95 | 0.31 |
Herson–Todd Scale (%) | 88 | 0.79 | Fair | 25 | 92 | 13 | 96 | 0.26 |
MeningiSSS (%) | 77 | 0.70 | Fair | 75 | 71 | 13 | 98 | 0.05 |
Niklasson Scale (%) | 88 | 0.72 | Fair | 0 | 94 | 0 | 94 | 0.57 |
Simple Luanda Scale (%)b | 99 | 0.63 | Poor | 40 | 90 | 18 | 97 | 0.04 |
Any adverse short-term outcomea | ||||||||
Aronin Scale (%) | 99 | 0.56 | Failed | 27 | 84 | 33 | 80 | 0.21 |
Herson–Todd Scale (%) | 88 | 0.53 | Failed | 18 | 93 | 38 | 83 | 0.17 |
MeningiSSS (%) | 77 | 0.63 | Poor | 44 | 73 | 33 | 81 | 0.17 |
Niklasson Scale (%) | 88 | 0.65 | Poor | 5 | 94 | 20 | 78 | 0.93 |
Simple Luanda Scale (%)c | 98 | 0.64 | Poor | 38 | 81 | 35 | 83 | 0.07 |
This table shows the Meningitis Swedish Survival Score’s (MeningiSSS) association with short-term outcome compared with existing predictive scores. First, the number of patients included for each predictive score (No.) is shown, followed by the area under the curve (AUC) obtained from the receiver operating curve characteristics analysis together with the performance category grading (Grade) based on this result [23]. Lastly, each predictive score’s sensitivity (Sens.), specificity (Spec.), positive predictive value (PPV), and negative predictive value (NPV) when tested at their cut-off levels using a Chi-square test are shown, including the p value of this analysis (pCut-Off)
aThis category comprises of patients with neurological disabilities at discharge defined as Pediatric Cerebral Performance Category Scale (PCPC) category two to five and patient that died (PCPC category six) [22]
bIn this analysis, the Simple Luanda Scale was tested using the cut-off level stated for predicting death
cIn this analysis, the Simple Luanda Scale was tested using the cut-off level stated for predicting adverse outcomes