Fig. 2.
PRx response to refractory intracranial hypertension expressed relative to changes in ICP (left) and CPP (right) (LOWESS with 95% confidence interval; n = 24). Pressure reactivity increased with increasing ICP and PRx plotted against CPP revealed a partial ‘U-shaped’ curve as previously described. PRx is well maintained until CPP drops below 70 mm Hg, below which PRx deteriorates. PRx pressure reactivity; ICP intracranial pressure; CPP cerebral perfusion pressure