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. 2020 Mar 19;70:18. doi: 10.1186/s12576-020-00745-2

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 4 — Attenuated contraction of the aortic rings from DKO mice. a Dose-dependent noradrenaline (NA)- and KCl b-induced isometric contraction of the aortic rings from C2α^flox/flox C2β^−/− (control) and DKO mice with and without the Rho kinase inhibitor Y-27632 (10 µM) was determined (n = 3 per each group). ^★p < 0.05, ^★★p < 0.01 and ^★★★p < 0.001 compared with control mouse rings