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The mechanism investigation suggests that mmu_circ_0000790 regulates the expression of FOXC1 and the Notch pathway through binding to miR-374c, thus affecting the biological characteristics of hypoxic PASMCs, such as proliferation, apoptosis, and migration. FOXC1, forkhead box C1; miR-374c, microRNA-374c; HPH, hypoxic pulmonary hypertension; PASMCs, pulmonary artery smooth muscle cells.
