Figure 2.

Irradiation and reconstitution results in a delay in B16F10 tumor growth dependent of initial radiation dose. 6 week old (A), age matched (B), or 7-11 Gy irradiated and reconstituted (C-E) C57Bl6 animals were implanted with 2 × 10⁵ B16F10 syngeneic melanoma tumor cells. In animals irradiated with 11 Gy, 5/9 tumors failed to engraft (E). In groups irradiated with 7 Gy and 9 Gy, all tumors (10/10) grew out. The growth rate of the tumors, however, was slower with increasing radiation doses (F). This figure is representative of at least two independent experiments.