Fig. 3.

Ligand interaction map of the predicted binding mode of A) 34, B) BI-D1870 R-isomer, C) 36, D) 33S-isomer, E) 33R-isomer, F) 24R-isomer, G) BI-D1870 S-isomer, H) 39R-isomer, I) 39S-isomer, J) 28R-isomer, K) 31R-isomer, and L) 35 in the ATP-binding site of the RSK2 NTKD, where red residues are charged negative, purple residues are charged positive, green residues are hydrophobic, and blue residues are polar, magenta arrows indicate H-bonds, violet lines indicate slat bridges, and gray spheres represent areas of solvent exposure.