Table 2.
Comparison of autofluorescence results and histopathological assessment.
| Diagnosis | No.of patients | Examination under velscope | Histopathological assessment | sensitivity | Specificity |
|---|---|---|---|---|---|
| Leukoplakia | 35 | All + ve | Neoplastic changes evident | 100% | – |
| Lichen planus | 16 | 14 +ve 2 -ve |
13 - mild dysplastic changes evident 3- no dysplastic change |
81% | 18% |
| Oral submucous fibrosis | 12 | 11 +ve 1 -ve |
10- mild dysplastic changes evident 2- no dysplastic change |
83% | 16% |
| Candidosis | 4 | 3 +ve 1 -ve |
3- minimal dysplastic changes evident 1- inflammatory changes seen. |
75% | 25% |
| Frictional keratosis | 8 | All + ve | 6 -carcinoma in situ 2- benign tissue |
75% | 25% |
| Smokers palate | 2 | All + ve | Carcinoma in situ | 100% | – |
| Coated tongue | 5 | All + ve | No dysplastic change | 0% | – |
| Erythroplakia | 20 | All + ve | Mild to moderate dysplastic changes evident | 100% | – |
| Mucositis | 2 | All + ve | No dysplastic change | 0% | – |
| Pigmented areas | 3 | All + ve | No dysplastic change | 0% | – |
| Geographic tongue | 3 | All + ve | No dysplastic change | 0% | – |