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Intraperitoneal (IP) therapeutic treatment with RTX. (A) SJL/J mice were induced to develop EAE (grey line). Mice also received 5 μg/mouse RTX IP upon first sign of disease appears usually on day 10 or 12 after disease induction, and continued every three days until the termination of the experiment (blue line). (B) Bodyweight of animals measured every day since the induction of the disease.
Abbreviations: EAE, experimental autoimmune encephalomyelitis; RTX, rituximab.
