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. 2020 Mar 10;15:1677–1691. doi: 10.2147/IJN.S225807

Figure 8.

Figure 8

Antitumor efficacy in vivo.

Notes: (A) The body weights of B16-F10 tumor-bearing mice after injection with PBS, free aPDL1, SSLs, aPDL1-SSLs, CAT@SSLs, and CAT@aPDL1-SSLs. (B) The relative tumor volume of mice in each group. (C) Survival curves of mice after treatment with the formulations described above. (n = 6, results means ± S.D., **P < 0.01, ***P < 0.001)

Abbreviations: aPDL1, programmed death ligand 1 monoclonal antibody; CAT, catalase; SSL, sterically stabilized liposome; aPDL1-SSLs, aPDL1 modified immunoliposomes; CAT@aPDL1-SSLs, CAT-loaded immunoliposomes.