Skip to main content
. 2020 Mar 18;13(4):100751. doi: 10.1016/j.tranon.2020.100751

Figure 1.

Figure 1

Effect of Enzalutamide and AS602801 on cell viability, proliferation, and cytotoxicity. LNCaP (A), C4-2 (B), or 22Rv1 (C) cells were plated 10,000 cells/well in 96-well plates and treated with ENZ, AS602801, or both and cell viability was assessed using RealTime Glo™ MT Cell Viability Assay. (D) Viability for LNCaP, C4-2, PC3, and DU145 cells over a range of concentrations of AS602801 is shown. (E) Proliferation of LNCaP cells was assayed by MTT at the indicated concentrations over a 5 day time course. (F) Cell death of LNCaP cells after 48 hr. incubation with ENZ (12.5 μM), AS602801 (7.5 μM), or both was measured using CellTox Green® assay, indicating strong synergy with the combination.