Table 2. Univariable and Multivariable Logistic Regression Analysis of Factors Associated with Diagnosis of NAFLD in Development Cohort.
| Variables | Univariable Analysis | Multivariable Analysis† | ||
|---|---|---|---|---|
| Odds Ratio (95% CI) | P | Adjusted Odds Ratio (95% CI) | P | |
| Age | 1.03 (1.02–1.04) | < 0.001 | ||
| Sex (female) | 0.44 (0.35–0.55) | < 0.001 | ||
| BMI | 1.34 (1.28–1.40) | < 0.001 | 1.17 (1.12–1.23) | < 0.001 |
| AST* | 5.40 (3.57–8.16) | < 0.001 | ||
| ALT* | 5.57 (4.32–7.17) | < 0.001 | 1.75 (1.31–2.36) | < 0.001 |
| Bilirubin | 1.18 (0.89–1.57) | 0.25 | ||
| ALP | 1.02 (1.01–1.02) | < 0.001 | ||
| Triglyceride* | 3.5 (2.85–4.30) | < 0.001 | 1.58 (1.31–2.08) | < 0.001 |
| Cholesterol | 1.02 (1.01–1.02) | < 0.001 | 1.01 (1.00–1.02) | < 0.001 |
| Glucose* | 8.40 (3.46–20.37) | < 0.001 | ||
| Albumin | 1.68 (1.17–2.40) | 0.005 | ||
| HDL-cholesterol | 0.96 (0.95–0.97) | < 0.001 | 0.98 (0.97–0.99) | < 0.001 |
| CTL-S | 0.84 (0.83–0.86) | < 0.001 | 0.87 (0.85–0.89) | < 0.001 |
Data in parentheses are range. *Analyzed after log transformation, †Multivariable analysis included candidate variables selected in more than 50% of logistic models from 1000-fold bootstrap resampling. CI = confidence interval, CTL-S = mean liver attenuation - mean spleen attenuation on non-enhanced CT, NAFLD = non-alcoholic fatty liver disease