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Fitness of a ciprofloxacin susceptible E. coli strain relative to fitness of an isogenic ciprofloxacin resistant strain across a gradient of ciprofloxacin for three LB broth treatments amended with Zn and one metal contaminated water source supplemented with LB. Horizontal dashed line indicates different strains perform equally well (ρs = ρr = 1), and the vertical lines represent the corresponding minimal selective concentration for the different Zn treatments.
