Table 5.
Effect of β-carotene (BC) on mortality by weight and alcohol intake in subgroup A (Alpha-Tocopherol Beta-Carotene Study 1985–1993)*
| Subgroup | Placebo | BC |
|---|---|---|
| All | ||
| RR | 1·0 | 2·29 |
| 95 % CI | Reference | 1·28, 4·1 |
| Deaths | 17 | 35 |
| Participants | 223 | 214 |
| Weight | ||
| <80 kg | ||
| RR | 1·0 | 4·4 |
| 95 % CI | Reference | 1·8, 11 |
| P | 0·0003 | |
| Deaths | 6 | 24 |
| Participants | 121 | 117 |
| ≥80 kg | ||
| RR | 1·0 | 1·1 |
| 95 % CI | Reference | 0·49, 2·6 |
| P | 0·8 | |
| Deaths | 11 | 11 |
| Participants | 102 | 97 |
| Alcohol | ||
| <14 g/d | ||
| RR | 1·0 | 1·6 |
| 95 % CI | Reference | 0·8, 3·5 |
| P | 0·2 | |
| Deaths | 12 | 16 |
| Participants | 113 | 98 |
| ≥14 g/d | ||
| RR | 1·0 | 3·9 |
| 95 % CI | Reference | 1·4, 11 |
| P | 0·003 | |
| Deaths | 5 | 19 |
| Participants | 110 | 116 |
RR, risk ratio.
*
This Table is limited to the placebo and BC arms of subgroup A of Table 3. The test of interaction between body weight and BC gives P = 0·02, and between alcohol and β-carotene gives P = 0·15.