Table 1.
C. albicans cell surface associated proteins important for binding with host complement proteins.
C. albicans protein | Binds with complement protein | References |
---|---|---|
Phosphoglycerate mutase (Gpm1p/GPM1) | Factor H, FHL-1, and plasminogen | (Poltermann et al., 2007; Lopez et al., 2014) |
pH-regulated antigen 1 (Pra1) | C4BP, C3 | (Luo et al., 2010, 2011, 2018) |
Translation elongation factor 1 (Tef1p) | FH, C4BP, C3d, C3dg | (Lopez, 2013) |
Glyceraldehyde-3-phosphate dehydrogenase (Gapdh) | FH and FHL-1, | (Luo et al., 2013a) |
High-affinity glucose transporter 1(CaHgt1p) | FH and C4BP | (Lesiak-Markowicz et al., 2011; Kenno et al., 2019) |