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. Author manuscript; available in PMC: 2020 Mar 20.
Published in final edited form as: ACS Appl Mater Interfaces. 2019 Aug 5;11(32):28740–28751. doi: 10.1021/acsami.9b10379

Figure 8.

Figure 8.

Fabrication of a multi-layer mucoadhesive patch and its mucoadhesive properties on porcine buccal mucosa tissue. (A) Schematic of the multi-layer mucoadhesive patch structure; (B) Photograph of as-fabricated multi-layer mucoadhesive patch; SEM images of (C) surface morphology and (D) cross-section morphology; (E) A photograph of adhered multi-layer mucoadhesive patch on a section of porcine buccal mucosa; (F) H&E staining of multi-layer mucoadhesive patch adhered to the porcine buccal mucosa; (G) Mucoadhesive forces between different samples and porcine buccal mucosa (n=3; *p < 0.05, **p < 0.01).