Table 4.
All-cause mortality, HCRU and costs after orthopedic surgery in patients with/without S. aureus infection
| Patients with SAI in the 365-d follow-up | Patients w/o SAI in the 365-d follow-up | p-value for differences between patients with/without SAI | |
|---|---|---|---|
| N | 1430 | 72,897 | |
| Patients who died | |||
| During index hospital stay,% | 0 | 1.27 | p < 0.001 |
| Within 30 d, % | 0.35 | 1.40 | p < 0.001 |
| Within 90 d, % | 4.90 | 2.79 | p < 0.001 |
| Within 180 d, % | 11.61 | 3.91 | p < 0.001 |
| Within 365 d, % | 22.38 | 5.31 | p < 0.001 |
| 365-d follow-up HCRU per patient-year | |||
| No. of outpatient GP visits, Mean (SD) | 3.17 | 3.20 | p = 0.566 |
| No. of outpatient specialist visits, Mean (SD) | 3.65 | 3.46 | p < 0.001 |
| No. of all-cause hospitalizations, Mean (SD) a | 3.06 | 0.70 | p < 0.001 |
| No. of hospital days, Mean (SD) a | 53.48 | 6.92 | p < 0.001 |
| No. of outpatient prescriptions of antibiotics, Mean (SD) | 2.17 | 0.63 | p < 0.001 |
| 365-d follow-up costs (€) per patient-year | |||
| Outpatient physician visits | 1149€ | 1011€ | p < 0.001 |
| Outpatient all-agent medication | 2605€ | 1327€ | p < 0.001 |
| Hospitalizations (incl. Inpatient drug treatment) b | 39,080€ | 11,444€ | p < 0.001 |
| Total costs | 42,834€ | 13,781€ | p < 0.001 |
Outcomes measured within 365 days after index surgical procedure, censoring at time of death
S aureus, Staphylococcus aureus, SAI Staphylococcus aureus infection, SD Standard deviation
aExcluding index hospitalization; bIncluding index hospitalization