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. 2020 Mar 19;20:234. doi: 10.1186/s12885-020-06749-w

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© The Author(s) 2020

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 1 — Electrophoretic separation of MTHFR, XRCC1 and OGG1 digestion in 3% Metaphor gel. Marker of molecular weight: Low Molecular Weight DNA Ladder (NEB). aMTHFR C677T: lane 1 TT (178, 23 bp), lanes 2, 4, 6 CC (201 bp), lane 6 CT (201, 178, 23 bp), lane 3 marker molecular weight; bMTHFR A1298C: lane 1 CC (84, 31, 30, 28, 18 bp), lanes 2 AA (56, 31, 30, 28, 18 bp), lane 3 AC (84, 56, 31, 30, 28, 18 bp), lane 4 marker molecular weight; cXRCC1 Arg194Trp (bold) and Arg399Gln PCR-multiplex: lane 1 arg/trp-arg/gln (615, 374, 313, 292, 241, 174 bp), lanes 2, 3, 7, 9, 11, 12 arg/arg-arg/arg (374, 292, 241, 174 bp), lane 5 arg/trp-arg/arg (374, 313, 292, 241, 174 bp), lane 6 arg/arg-gln/gln (615, 292, 174 bp), lanes 8,10 arg/arg-arg/gln (615, 374, 292, 241, 174 bp), lanes 4, 13 marker molecular weight. d. OGG1 Ser326Cys: lane 1 marker molecular weight, lane 2 ser/cys (213, 164, 49, 21 bp), lane 3 ser/ser (213, 21 bp), lane 4 cys/cys (164, 49, 21 bp)