Table 4.

Aplotype frequencies of MTHFR and XRCC1 in BC patiens and controls D’ and r2 statistics calculated in 1000 genomes European population

Gene	Haplotype		Cases	Controls	OR (95% CI)	p
MTHFR D’ = 0.9999 r2 = 0.262	rs1801133	rs1801131
	T	A	95 (38.52%)	110 (44.64%)	1.00
	C	C	77 (31.11%)	70 (28.12%)	1.27 (0.83–1.95)	0.27
	C	A	75 (30.37%)	67 (27.23%)	1.30 (0.84–1.99)	0.24
	T	C	0.00	0.00	–	–
XRCC1 D’ = −0.9997 r2 = 0.031	rs1799782	rs25487
	C	G	160 (64.81%)	153 (62.05%)	1.00
	C	A	81 (32.59%)	83 (33.48%)	0.92 (0.63–1.34)	0.67
	T	G	6 (2.59%)	11 (4.46%)	0.52 (0.19–1.45)	0.21
	T	A	0.00	0.00