TABLE 1.
Surface proteins of Erysipelothrix rhusiopathiae with a suspected role in immunogenicity.
| Locus tag | Nucleotide | Amino acid | |||||
| Gene | Name/Description | (former) | Positionsa | length | length | References | |
| 1 | spaAb | Choline-binding protein | ERH_RS00500 (ERH_0094) | 112,931–114,811 | 1881 | 626 | Imada et al., 1999; Shimoji et al., 1999 |
| 2 | rspA | Rhusiopathiae surface protein A; B-type domain-containing protein; LPXTG-motif cell wall anchor | ERH_RS03410 (ERH_0668) | 701,546–707,524 | 5979 | 1992 | Shimoji et al., 2003 |
| 3 | CbpB | Choline-binding protein | ERH_RS03905 (ERH_0768) | 813,020– 814,840 | 1821 | 606 | Shi et al., 2013; Zhu et al., 2018 |
| 4 | GAPDH (gapA) | type I glyceraldehyde-3-phosphate dehydrogenase | ERH_RS07885 (ERH_1534) | 1,618,401–1,619,405 (rev) | 1005 | 334 | Shi et al., 2013; Zhu et al., 2018 |
| 5 | Da (dap2) | Dipeptidyl aminopeptidase; S9 family peptidase | ERH_RS00295 (ERH_0059) | 62355–64328 (rev) | 1974 | 657 | Hu et al., 2017 |
| 6 | CbpA | Collagen-binding protein; cell wall anchor | ERH_RS00405 (ERH_0075) | 89263–94584 | 5322 | 1773 | Hu et al., 2017 |
| 7 | Plp | Pectin lyase fold-containing protein | ERH_RS00860 (ERH_0165) | 196,260–200,819 | 4560 | 1519 | Hu et al., 2017 |
| 8 | Atsp | ABC transporter, extracellular solute-binding protein | ERH_RS01215 (ERH_0228) | 262,816–264,261 | 1446 | 481 | Hu et al., 2017 |
| 9 | Neu (nanH) | Neuraminidase; LPXTG-motif cell wall anchor domain protein | ERH_RS01540 (ERH_0299) | 331,513–335,127 (rev) | 3615 | 1204 | Hu et al., 2017 |
| 10 | Bga | Beta-galactosidase; DUF4982 domain-containing protein | ERH_RS03965 (ERH_0780) | 825,779–832,054 | 6276 | 2091 | Hu et al., 2017 |
| 11 | Bml | Basic membrane lipoprotein; BMP family ABC transporter substrate-binding protein | ERH_RS05080 (ERH_1005) | 1,061,289–1,062,380 (rev) | 1092 | 363 | Hu et al., 2017 |
| 12 | CwpA | LPXTG-motif cell wall anchor domain protein | ERH_RS07320 (ERH_1428) | 1,500,578–1,506,982 (rev) | 6405 | 2134 | Hu et al., 2017 |
| 13 | CwpB | LPXTG-motif cell wall anchor domain protein | ERH_RS07450 (ERH_1454) | 1,537,616–1,540,657 (rev) | 3042 | 1013 | Hu et al., 2017 |
All listed proteins have experimentally been shown to be involved in eliciting a host immune response. aPositions are in relationship with reference strain Fujisawa (NC_015601). bspaB and spaC sequences, with a role in immunogenicity of Erysipelothrix spp., were not found in any of the isolates in this study.