Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Mar 13;10:311. doi: 10.3389/fonc.2020.00311

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

Copyright © 2020 Yue, Zhang, Shi, Liu, Li, Wang, Qin, Ping, Qiao, Chen, Wang, Chen, Zhao, Wang and Zhang.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

PMC Copyright notice

Chloroquine targeted CXCR4-positive ESCC cells via STAT3. (A) The expression of CXCR4 was analyzed by flow cytometry. (B) The activity of pSTAT3 and tSTAT3 were measured by western blotting in ESCC cells with or without CQ treatment (5 μM). (C) The expression of CXCR4 was analyzed by flow cytometry in ESCC cells with or without STAT3 inhibitor (S3I-201, Sigma, USA) treatment. (D) The expression analysis of ATG7 and BECN1 was detected by real time PCR in ESCC cells with or without CQ treatment (5 μM). (E) The expression of CXCR4 was analyzed by flow cytometry in ESCC cells after ATG7 or BECN1 knockdown. *P < 0.05.