Skip to main content
. Author manuscript; available in PMC: 2020 Mar 20.
Published in final edited form as: Trends Cell Biol. 2018 Nov 29;29(3):191–200. doi: 10.1016/j.tcb.2018.11.002

Figure 2:

Figure 2:

Short poly(A) tails are associated with highly expressed, well-translated transcripts. These shortened tails occur at discrete lengths that have a phasing pattern matching the footprint of serial binding of cytoplasmic poly(A) binding protein. Longer tails do not show this phasing and have less well-defined tails. In somatic cells, short tailed transcripts tend to have high codon optimality and long half lives.