. 2020 Mar 13;11:216. doi: 10.3389/fgene.2020.00216

TABLE 4.

Least-squares means ± standard errors for changes of white blood cell traits¹ between Blood 1, 3, and 4 of animals in the resilient (RES), average (MID), susceptible (SUS), and dead (DEAD) groups.

Δ13², 10³/μL	RES	MID	SUS	DEAD	FDR-group⁵
WBC	8.39 ± 0.39^a6	7.68 ± 0.17^a	7.10 ± 0.40^a	7.74 ± 0.29^a	0.24
NEU	5.52 ± 0.27^a	5.52 ± 0.11^a	5.35 ± 0.29^a	5.93 ± 0.20^a	0.38
LYM	1.69 ± 0.17^b7	0.85 ± 0.07^a	0.67 ± 0.17^a	0.51 ± 0.12^a	<0.0001
MONO	0.56 ± 0.03^a	0.49 ± 0.01^a	0.42 ± 0.03^a	0.47 ± 0.02^a	0.08
EOS	0.23 ± 0.04^a	0.26 ± 0.01^a	0.18 ± 0.04^a	0.24 ± 0.03^a	0.38
BASO	0.85 ± 0.08^a	0.66 ± 0.04^a	0.63 ± 0.07^a	0.79 ± 0.06^a	0.08
Δ34³, 10³/μL	RES	MID	SUS	DEAD	FDR-group
WBC	2.13 ± 0.51^a	2.89 ± 0.23^a	4.06 ± 0.54^a	3.91 ± 0.68^a	0.08
NEU	−0.60 ± 0.41^a	−0.33 ± 0.17^a	1.36 ± 0.40^b	1.77 ± 0.51^b	<0.0001
LYM	3.08 ± 0.25^a	3.41 ± 0.11^a	3.24 ± 0.26^a	2.78 ± 0.32^a	0.32
MONO	0.16 ± 0.05^a	0.20 ± 0.02^a	0.24 ± 0.05^a	0.13 ± 0.06^a	0.65
EOS	−0.08 ± 0.04^a	−0.13 ± 0.02^a	−0.04 ± 0.04^a	−0.03 ± 0.06^a	0.16
BASO	−0.54 ± 0.06^a	−0.45 ± 0.03^a	−0.38 ± 0.06^a	−0.40 ± 0.08^a	0.42
Δ14⁴, 10³/μL	RES	MID	SUS	DEAD	FDR-group
WBC	10.39 ± 0.48^a	10.75 ± 0.19^a	11.60 ± 0.51^a	11.73 ± 0.63^a	0.27
NEU	4.75 ± 0.35^a	5.11 ± 0.14^a	6.83 ± 0.36^b	7.32 ± 0.45^b	<0.0001
LYM	4.63 ± 0.23^a	4.37 ± 0.09^a	4.06 ± 0.24^a	3.56 ± 0.31^a	0.08
MONO	0.72 ± 0.04^a	0.71 ± 0.02^a	0.66 ± 0.04^a	0.61 ± 0.05^a	0.37
EOS	0.12 ± 0.03^a	0.13 ± 0.01^a	0.22 ± 0.03^a	0.19 ± 0.04^a	0.12
BASO	0.15 ± 0.03^a	0.20 ± 0.01^a	0.24 ± 0.02^a	0.23 ± 0.03^a	0.12

¹WBC: total white blood cell concentration; NEU: neutrophil concentration; LYM: lymphocyte concentration; MONO: monocyte concentration; EOS: eosinophil concentration; BASO: basophil concentration. ²The change of complete blood count (CBC) traits from Blood 1 to Blood 3; ³The change of CBC traits from Blood 3 to Blood 4; ⁴The change of CBC traits from Blood 1 to Blood 4. ⁵FDR-group: adjusted p-values for the significant level of group effect using the Benjamini and Hochberg correction (FDR) in R to control false positives from multiple comparisons (R Core Team, 2017 Package ‘stats’). ⁶Values in a column suffixed with different letters are significantly different from each other at FDR < 0.05. ⁷Significant differences among RES, MID, SUS and DEAD groups are highlighted in bold (FDR < 0.05).