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. 2020 Mar 13;10:294. doi: 10.3389/fonc.2020.00294

Figure 2.

Figure 2

miR-1224-5p inhibits the migration and invasion of CRC cells in vitro. (A) SW480 and HCT116 cells that were transfected with miR-1224-5p-inhibitor and miR-1224-5p-mimics lentivirus were subjected to qRT-PCR for miR-1224-5p. (B,C) Effects of miR-1224-5p on migration in CRC cell lines were detected by wound healing assay, scale bars: 300 μm. (D). Cell migration and invasion as measured by Transwell assays were promoted by miR-1224-5p knockdown in SW480 cells, scale bars: 100 μm. (E) miR-1224-5p overexpression inhibited migration and invasion of HCT116 cells, scale bars: 50 μm. Data represent the mean ± SD from three independent experiments. Student's t-test was used to determine statistical significance: *p < 0.05, **p < 0.01, and ***p < 0.001.