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. 2020 Mar 13;10:294. doi: 10.3389/fonc.2020.00294

Table 1.

Expression of miR-1224-5p and SP1 according to patients' clinical features.

Characteristics Number miR-1224-5p expression P-value SP1 expression P-value
High group Low group High group Low group
Age (years)
<50 16 7 9 0.58 6 10 0.26
>50 64 33 31 34 30
Gender
Female 48 26 22 0.36 23 25 0.65
Male 32 14 18 17 15
Lymph node metastasis
No 47 30 17 0.003** 16 31 <0.001***
Yes 33 10 23 24 9
Tumor stage
Stage I, II 37 25 12 0.004** 10 27 <0.001***
Stage III, IV 43 15 28 30 13
TNM staging system
T1+T2 45 30 15 <0.001*** 13 32 <0.001***
T3+T4 35 10 25 27 8
Distant metastasis
No 62 35 27 0.03* 26 36 0.007**
Yes 18 5 13 14 4
Tumor size(cm)
<3 cm 48 23 25 0.65 20 28 0.06
>3 cm 32 17 15 20 12
*

P < 0.05,

**

P < 0.01, and

***

P < 0.001.