Figure 2.
SIRT1 in CeA neurons is involved in emotional pain vulnerability. A–C, Western blots (top) and group data (bottom) of SIRT1, SIRT2, SIRT6, and β-actin proteins in the CeA in sham rats and CCI-ION rats 28 d after the sham or CCI-ION surgery. D, Western blots (top) and group data (bottom) of SIRT1 and β-actin proteins in the CeA of sham rats, anxiety-vulnerable CCI-ION rats (n = 17), and anxiety-resistant CCI-ION rats (n = 5). E, Similar data of CeA SIRT1 and β-actin proteins in sham rats, in depression-vulnerable CCI-ION rats (n = 18), and in depression-resistant CCI-ION rats (n = 4). N = 22 both in the sham group and in the CCI-ION group. **p < 0.01.