Table 2. Baseline characteristics of all patients with r-axSpA and nr-axSpA at recruitment in SCQM.
Parameter | nr-axSpA N = 431 | r-axSpA N = 1155 | P |
---|---|---|---|
Female sex, % | 53.8 | 30.6 | <0.001 |
Age, years | 37.1 (10.8) | 40.3 (11.3) | <0.001 |
Symptom duration, years | 8.8 (9.4) | 15.0 (11.1) | <0.001 |
HLA-B27 positive, % | 73.1 | 81.5 | <0.001 |
BASDAI | 5.0 (2.2) | 4.7 (2.2) | 0.14 |
ASDAS | 2.9 (0.9) | 3.1 (1.1) | 0.02 |
CRP (mg/l), median (IQR) | 4.5 (2.0; 8.0) | 8.0 (3.0; 15.0) | <0.001 |
Elevated CRP, % | 27.9 | 48.1 | <0.001 |
BASFI | 3.1 (2.4) | 3.6 (2.6) | <0.001 |
BASMI | 1.3 (1.3) | 2.5 (2.2) | <0.001 |
EQ-5D | 59.6 (20.9) | 60.4 (22.4) | 0.49 |
Current peripheral arthritis, % | 38.7 | 31.6 | 0.01 |
Current enthesitis, % | 73.5 | 65.1 | 0.002 |
On methotrexate, % | 7.9 | 7.6 | 0.83 |
On sulfasalazine, % | 5.3 | 4.8 | 070 |
On NSAIDs, % | 89.5 | 88.6 | 0.64 |
On TNFi, % | 13.9 | 22.8 | 0.002 |
Current smokers, % | 31.1 | 40.6 | 0.001 |
BMI | 24.7 (4.2) | 25.3 (4.5) | 0.01 |
Number exercise sessions per week, median (IQR) | 2.0 (0.0; 4.0) | 2.0 (0.0; 4.0) | 0.92 |
Values are the mean (SD), except where indicated otherwise. ASDAS = Ankylosing Spondylitis Disease Activity Score; BASDAI = Bath Ankylosing Spondylitis Disease Activity Index; BASFI = Bath Ankylosing Spondylitis Functional Index; BASMI = Bath Ankylosing Spondylitis Metrology Index; C-reactive protein (CRP) levels; EQ-5D = EuroQol 5-domain; HLA-B27 = human leucocyte antigen B27; MASES = Maastricht Ankylosing Spondylitis Enthesitis Score; modification refers to the inclusion of the plantar fascia in the count; nr-axSpA = nonradiographic axial spondyloarthritis; NSAIDs = Nonsteroidal anti-inflammatory drugs; r-axSpA = radiographic axial spondyloarthritis; TNFi = Tumour necrosis factor inhibitor.