TABLE 2: Comparisons of demographic and epidemiological data between hospitalized patients with influenza (N=46) and other CRV infections (N=398), 2012-2013.
| Influenza | Other CRVs | Unadjusted analysis | Adjusted analysis | |||
|---|---|---|---|---|---|---|
| Number positive/total | Number positive/total | p value | p value | OR | CI 95% | |
| (%) | (%) | |||||
| Virus co-infection | 8/46 (17.4) | 116/398 (29) | 0.115a | - | - | - |
| Sex | ||||||
| Male | 25/46 (54) | 204/398 (51) | 0.89a | - | - | - |
| Age, years | <0.0 b | - | - | |||
| <2 | 16/46 (35) | 290/398 (73) | - | - | - | - |
| 2 to 5 | 6/46 (13) | 35/398 (9) | - | - | - | - |
| 5 to 14 | 3/46 (7) | 22/398 (6) | - | - | - | - |
| 14 to 60 | 17/46 (37) | 39/398 (9) | - | - | - | - |
| >60 | 4/46 (8) | 12/398 (3) | - | - | - | - |
| Median age (IQR 25-75) | 5.4 (0.6-42) | 0.7 (0.2-2.3) | <0.01 c | 0.003 | 1.022 | 1.007-1.037 |
| Nosocomial Infection | 2/46 (4) | 51/398 (13) | 0.145b | - | - | - |
| Time of hospitalization, days | ||||||
| Median, (IQR 25-75) | 8.5 (6-13.2) | 7 (4-16) | 0.18c | - | - | - |
| Influenza Vaccine (<1 year) | 12/46 (26) | - | NA | - | - | - |
| Use of oseltamivir | 16/46 (35) | - | NA | - | - | - |
| Clinical findings | ||||||
| Fever | 43 (93) | 311 (78) | <0.01b | 0.42 | - | - |
| Cough | 46 (100) | 353 (89) | 0.08b | 0.46 | - | - |
| Dyspnea | 43 (93) | 347 (87) | 0.33b | - | - | - |
| Myalgia | 11 (24) | 14 (4) | <0.01 b | <0.01 | 5.582 | 2.187-13.898 |
| Comorbidities | ||||||
| None | 26 (56) | 266 (66) | 0.21a | - | - | - |
| Immunosuppression | 10/26 (38) | 62/132 (47) | 0.35a | - | - | - |
| Chronic lung disease | 11/26 (42) | 53/132 (40) | 0.07a | - | - | - |
| Radiographic findings | ||||||
| Missing value | 13 (28) | 188 (47) | - | - | - | - |
| Normal | 2/33 (6) | 37/210 (17) | 0.12b | - | - | - |
| Interstitial infiltrate | 12/33 (36) | 68/210 (32) | 0.69b | - | - | - |
| Pulmonary consolidation | 9/33 (25) | 57/210 (27) | 1.00b | - | - | - |
| Mixed pattern | 9/33 (25) | 12/210 (5) | 0.04 b | 0.81 | - | - |
| Mechanical ventilation | 13 (28) | 82 (21) | 0.31a | - | - | - |
| ICU stay | 18 (39) | 129(32) | 0.45a | - | - | - |
| Died | 4 (9) | 22 (6) | 0.33b | - | - | - |
| Diagnosis of SARI | 41 (89) | 298 (75) | 0.04 a | 0.05 | - | - |
In bold: statistically significant; CRV: community-acquired respiratory virus; IQR: interquartile range; ICU: intensive care unit; ARD: acute respiratory distress; NA: not applicable; OR: odds ratio. aChi-squared test. bFisher’s exact test. cMann-Whitney U test.