Table 2.
Predictors of reaching maximum recommended dose of sacubitril‐valsartan
| Univariate | Multivariable | |||
|---|---|---|---|---|
| OR (95% CI) | P‐value | OR (95% CI) | P‐value | |
| Age (years) | 0.99 [0.97, 1.01] | 0.23 | 1.01 [0.99, 1.04] | 0.34 |
| Male | 1.04 [0.61, 1.78] | 0.87 | 0.75 [0.38, 1.47] | 0.400 |
| Baseline log NT‐proBNP | 0.81 [0.66, 1.01] | 0.056 | 0.85 [0.67, 1.09] | 0.210 |
| Baseline eGFR | 1.02 [1.01, 1.03] | 0.002 | 1.02 [1, 1.04] | 0.029 |
| Baseline haemoglobin | 1.21 [1.04, 1.4] | 0.015 | 1.14 [0.95, 1.36] | 0.160 |
| Diuretic dose decrease | 1.77 [1.05, 2.97] | 0.031 | 2.1 [1.16, 3.8] | 0.014 |
Abbreviations: CI, coefficient interval; NT‐proBNP, N‐terminal pro B‐type natriuretic peptide; OR, odds ratio; TD, target dose.