Summary of findings'. 'Summary of findings table.

What is the test accuracy of thromboelastography (TEG) and rotational thromboelastometry (ROTEM) for trauma‑induced coagulopathy (TIC) in adult trauma patients with bleeding?
Patients	Adult trauma patients with bleeding at risk of TIC
Prior testing	None
Setting	Hospital; civilian or military
Index tests	Tests of global haemostatic function especially thromboelastography (TEG) and rotational thromboelastometry (ROTEM). Any device output measure considered
Reference standard	Prothrombin ratio or International Normailsed ratio 1.2 or greater Prothrombin ratio or International Normailsed ratio 1.5 or greater
Study design	Cross‐sectional or case‐control test accuracy studies; all included studies were cross‐sectional
Test	No of participants (no. of studies)	Accuracy (sensitivity (95% CI))	Accuracy (specificity (95% CI))	Risk of bias	Implications
ROTEM EXTEM Clot amplitude 5 minutes (CA5)	409 (2)	Davenport 2011a: 70% (47,87) Woolley 2012: 96% (88,100)	Davenport 2011a: 86% (82,90) Woolley 2012: 58% (44,72)	High	Accuracy estimates potentially misleading
ROTEM EXTEM Clot amplitude 10 minutes (CA10)	109 (1)	100% (94,100)	70% (56,82)	High	Accuracy estimates potentially misleading
ROTEM EXTEM Clot amplitude 15 minutes (CA15)	88 (1)	88% (69,97)	100% (94,100)	High	Accuracy estimates potentially misleading

Concerns about risk of bias arose from consideration of the index test and the reference standard