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. 2020 Mar 20;6(12):eaaz0007. doi: 10.1126/sciadv.aaz0007

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Copyright © 2020 The Authors, some rights reserved; exclusive licensee American Association for the Advancement of Science. No claim to original U.S. Government Works. Distributed under a Creative Commons Attribution NonCommercial License 4.0 (CC BY-NC).

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Fig. 1 — (A) Schematic of the biomarker information delivery pathway enabled by the FESS, illustrating sampling, sensing, and routing of epidermally retrieved biomarker information to readout electronics through a single entity. (B) Design rationale of the FESS. (C) Representative implementation of the FESS, demonstrating flexibility and no in-plane interconnection. (D) Representative family of FESS devices, containing 1 × 2, 3 × 3, and 6 × 6 electrode arrays. (E) Custom-developed and FESS-enabled smartwatch for biomarker monitoring. (F and G) Deployment of the FESS-enabled smartwatch in stationary (F) and high-intensity exercise (G) settings. (Photo credit: Peterson Nguyen, Kaili Chiu, Yichao Zhao, University of California, Los Angeles.)