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. 2020 Mar 16;13:73–86. doi: 10.2147/CEG.S232961

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© 2020 Kaur et al.

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Gene–Gene interaction map for esophageal cancer risk: Values inside nodes indicate information gain (IG) of individual attributes or main effects, whereas values between nodes show IG of pairwise combinations of attributes or interaction effects. Positive entropy (red) indicates strong interaction (not found), (yellow) weak interaction while negative entropy (green) indicates redundancy and blue shows no interactions.

Notes: SNP1: XRCC1 p.Arg399Gln, SNP2: XRCC1 p.Arg194Trp, SNP3: XRCC1 p.Arg280His, SNP4: XRCC2 Arg188His, SNP5: XRCC2 p.Thr241Met.