Figure 1:

Sequence design used in this study with a train of flip angles (top) for each TR according to the IRFF sequence (blue) and optional MT pulses for the IRFF-MT design (red). The RF pulse train is separated into four segments (2x FLASH and 2x FISP) with gaps that allow for relaxation or to provide the space to play out the MT pulses. The phase of the pulses is shown in the middle with a quadratically increasing pulse phase for the last two FLASH segments. The off-resonance frequencies for the pulses are shown on the bottom.