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. 2019 Jun 6;7(2):253–265. doi: 10.1016/j.gendis.2019.05.002

Figure 2.

Figure 2

Effect of TBI on IL-6, NO and caspase-3 in CSF and serum. Collection of serum and cerebrospinal fluid in patients during the acute phase of TBI (within 6 h) and during the recovery phase (3 months after surgery). (A–B) IL-6 was evaluated using the IL-6 assay kit from CSF and serum samples. (C–D) The NO concentration was evaluated with an assay kit from CSF and serum samples. (E–F) Effect of TBI on caspase-3 production in CSF and serum. Data are expressed as the mean ± SD and asterisks indicate statistically significant differences between the TBI (n = 45) and Normal groups (n = 30). *p < 0.05, **p < 0.01 (t-test).