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(A) Schematic illustration of the preparation of UCNP–Ce6-aptamer and its ROS generation principle. (B) TEM images of UCNP with DNA conjugation, the emission spectrum of UCNP (black line) and UV-vis absorption spectrum of Ce6 (red line), and monitoring 1O2 generation of UCNP-Ce6-sgc8 upon 980 nm laser irradiation, in sequence from left to right. (C) PDT efficacy of CEM cells treated with UCNP-Ce6-sgc8 [227].
