Table 3.

List of the AUC Scores Obtained by Various Methods on the On-Target Dataset Reported in Chuai et al.⁴⁶

Cell Typea	Methods	AUC (%)
hct116	Azimuthb	74.1
	DeepCRISPR (pt+aug CNN)c	87.4
	sgRNA-PSMd	91.7
	Retrained sgRNA-PSMe	74.0
Hela	Azimuthb	67.5
	DeepCRISPR (pt+aug CNN)c	78.2
	sgRNA-PSMd	82.8
	Retrained sgRNA-PSMe	72.1
hl60	Azimuthb	79.2
	DeepCRISPR (pt+aug CNN)c	73.9
	sgRNA-PSMd	77.6
	Retrained sgRNA-PSMe	83.7

^aThe cell type of the independent test dataset.

^bResults reported in Chuai et al.⁴⁶

^cResults reported in Chuai et al.⁴⁶

^dThe sgRNA-PSM predictor trained with the dataset reported in Chuai et al.;⁴⁶ see Equations 9 and 10 with k = 4, m = 2,$\complement$ = 9, R = 0.05, F = 2,300.

^eThe sgRNA-PSM predictor trained with each of the three datasets (hct116, hela, and hl60).