Table 2.

Infarct thresholds of several mouse and rat strains (suture method)

Species, strain	rCBF during occlusion (%)	Infarct threshold	The duration of MCAO for TIA model (min)
Rat, SD [18]	20	10 min Hippocampal infarcts were observed in 33.3% (2/6) of rats*	< 5
Rat, Wistar [20]	24	12.5 min Caudate nucleus infarcts were observed in 16.7% (1/6) of rats*	< 10
Mouse, NMRI [35]	15	12.5 min Cortical infarcts were observed in 16.7% (1/6) of mice*	< 10
Mouse, ICR-CD1 [36]	15	10 min Striatal infarcts were observed in 50.0% of mice*	< 10
Mouse, C57BL/6 [37]	34	No infarcts were found in any mice after MCAO for 5 min*

rCBF relative cerebral blood flow, which is the percentage of CBF in the basal CBF

*Infarcts that were confirmed by MRI; as shown in the table, 10 min can be selected for TIA-related study in the pre-experiment