Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2020 Mar 20;10:101. doi: 10.1038/s41398-020-0782-1

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — a, b The distance traveled in the center square (one-way ANOVA: F(2, 21) = 3.668, p = 0.043; Post-hoc test: SPS&S + ZD7288: p = 0.179, SPS&S + 8-Br-cAMP: p = 0.026) and total distance (one-way ANOVA: F(2, 21) = 4.924, p = 0.018; Post-hoc test: SPS&S + ZD7288: p = 0.811, SPS&S + 8-Br-cAMP: p = 0.014) in OFT. c, d The entries in the open arms (one-way ANOVA: F(2, 21) = 5.340, p = 0.013; Post-hoc test: SPS&S + ZD7288: p = 0.720, SPS&S + 8-Br-cAMP: p = 0.010) and total arm entries (one-way ANOVA: F(2, 21) = 3.592, p = 0.046; Post-hoc test: SPS&S + ZD7288: p = 0.128, SPS&S + 8-Br-cAMP: p = 0.711) in EPMT. e The passive activity time in FST (one-way ANOVA: F(2, 21) = 23.944, p = 0.000; Post-hoc test: SPS&S + ZD7288: p = 0.000, SPS&S + 8-Br-cAMP: p = 0.000). f, g The escape latency time in place navigation test (MANOVA: F(6, 63) = 5.902, p = 0.000; SPS&S + ZD7288:the second day: p = 0.001 and third day: p = 0.001; SPS&S + 8-Br-cAMP: the second day: p = 0.030 and fourth day: p = 0.000)and time spend in training quadrant in spatial probe test (one-way ANOVA: F(2, 21) = 0.251, p = 0.781; Post-hoc test: SPS&S + ZD7288: p = 0.855, SPS&S + 8-Br-cAMP: p = 0.963) of WMT. h–m Representative video tracking images during EMPT and OFT, h, k SPS&S + Vehicle group, i, l SPS&S + ZD7288 group, j, m SPS&S + 8-Br-cAMP group. Data are represented as mean ± SEM. *p < 0.05 was expressed statistically significant. *p < 0.05, **p < 0.01, and ***p < 0.001 compared with SPS&S + Vehicle group.