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. 2020 Mar 20;10:5178. doi: 10.1038/s41598-020-62088-7

Table 1.

IC50 (cell viability) values of compounds affecting the ubiquitin proteasome machinery in imatinib (IM)-sensitive and IM-resistant GIST cells.

IC50 (nM)
CFZ IXA DLZ BO
GIST882 184 82 23 13
GIST-T1 1,679 175 36 26
GIST48 67 41 9 7
GIST430 185 56 12 13

CFZ, carfilzomib; IXA, ixazomib; DLZ, delanzomib; BO, bortezomib. GIST882, GIST-T1 (IM-sensitive); GIST48, GIST430 (IM-resistant).