Table 2.
Elemental concentrations (mg/g protein) in lysates prepared from homogenisation of medial temporal cortical tissue from cognitively normal (CN) and Alzheimer’s disease (AD) subjects. Data are presented as mean ± standard deviation (sample size). Significance was set at *p ≤ 0.05, and t-value and degrees of freedom (df) shown. Elemental concentrations differing significantly differently between CN and AD are in bold.
| CN(n) mg/g protein |
AD(n) mg/g protein |
p-value | t-value (df) | |
|---|---|---|---|---|
| Iron | 3.503 ± 1.579 (7) | 3.195 ± 0.653 (6) | 0.6496 | 0.472 (8.238) |
| Copper | 0.270 ± 0.110 (7) | 0.246 ± 0.105 (7) | 0.6803 | 0.422 (11.98) |
| Zinc | 0.742 ± 0.174 (7) | 0.556 ± 0.108 (6) | 0.0411* | 2.338 (10.15) |
| Calcium | 5.296 ± 1.808 (7) | 5.092 ± 1.032 (7) | 0.1977 | 0.259 (9.531) |
| Phosphorus | 214.00 ± 52.00 (7) | 200.00 ± 36.00 (7) | 0.5786 | 0.573 (10.77) |