Table 6.

The impact of clinical factors on glioma patient OS and PFS.

Variables		Total	Event	OS				PFS
				Log-rank P	SR (1-/3-year)	HR (95%CI)	P	FDR- P	Log-rank P	SR (1-/3-year)	HR (95%CI)	P	FDR- P
Sex	Male	313	278	0.379	0.328/0.082	1.08 (0.92–1.28)	0.420	0.490	0.268	0.200/0.096	1.09 (0.92–1.30)	0.321	0.321
	Female	255	229		0.310/0.094					0.155/0.089
Age	<40	250	215	0.074	0.355/0.117	1.16 (0.97–1.38)	0.101	0.235	0.064	0.206/0.119	1.16 (0.97–1.38)	0.097	0.136
	≥40	317	291		0.290/0.067					0.159/0.072
WHO grade	I + II	355	311	0.121	0.328/0.108	1.14 (0.95–1.36)	0.155	0.271	0.096	0.192/0.108	1.15 (0.96–1.37)	0.136	0.159
	III + IV	213	196		0.305/0.064					0.158/0.067
Surgery	NTR & STR	181	178	1.54E-07	0.204/−	0.63 (0.53–0.77)	1.88E-06	1.32E-05	1.91E-09	0.016/−	0.59 (0.49–0.71)	6.78E-08	4.75E-07
	GTR	387	329		0.374/0.123					0.254/0.126
Radiotherapy	No	59	48	0.438	0.441/−				0.118	0.200/−			0.136
Conformal radiotherapy		154	126		0.250/0.152	1.08 (0.78–1.51)	0.636	0.636		0.217/0.154	1.37 (0.97–1.94)	0.070
	Gamma knife	355	333		0.330/0.055	1.17 (0.87–1.59)	0.303	0.424		0.163/0.058	1.31 (0.96–1.80)	0.090	0.136
Chemotherapy	No	337	315	1.38358E-05	0.276/0.029	0.69 (0.58–0.83)	7.46734E-05	0.000261	0.005	0.164/0.057	0.79 (0.66–0.95)	0.011	0.039
	Yes	231	192		0.384/0.151					0.205/0.155

OS, overall survival; PFS, progression free survival; SR, survival rate; HR, hazard ratio; CI, confidence interval; WHO, World Health Organization; STR, sub-total resection; NTR, near-total resection; GTR, gross-total resection; FDR, false discovery rate.

Bold values indicate statistical significance (P < 0.05).