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. 2020 Mar 20;10:5164. doi: 10.1038/s41598-020-62026-7

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© The Author(s) 2020

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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ROIs showing differences in brain activation between low and high PLEs groups. Coronal View; Horizontal Axis: Left = Left, Right = Right; Vertical Axis: Up=Superior, Down=Inferior. Colour Coding. Age 14-[42 8 −14]: Right Insular Cortex (H > L) [shown in green]. [−36 11 −5]: Left Insular Cortex (L > H) [shown in purple]. Age 19-[−12 5 10]: Left Caudate Body (L > H) [shown in blue]. [6 65 31]: Right Superior Frontal Gyrus (L > H) [shown in red].[33 −46 −5]: Right Parahippocampal Gyrus/Amygdala (L > H) [shown in yellow].