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. 2020 Mar 2;117(11):6067–6074. doi: 10.1073/pnas.1904532117

Fig. 4.

Fig. 4.

The effect of GHRH-R activities on modulating STAT3 phosphorylation. (A) The GHRH-R agonist MR-409 (1 µM) increased phosphorylation of STAT3 in human ciliary epithelial cells. (B) The GHRH-R antagonist MIA-602 (1 µM) suppressed STAT3 phosphorylation. (C) MR-409 attenuated the Ruxolitinib-mediated inhibition on STAT3. *P < 0.05; **P < 0.01; n.s., not significant; n = 4.