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Summary. Schematic illustration of stepwise, RNA-driven displacement of σ-finger with (A) primary σ-factor in primer-dependent transcription initiation (Fig. 1), (B) primary σ-factor in primer-independent transcription initiation (Fig. 2), (C) ECF σ-factor σH (Fig. 3), and (D) ECF σ-factor σL (Fig. 4). Colors as in Fig. 1. Disordered σ-finger segments are shown as dotted orange line and disordered 5′-triphosphate RNA phosphates are omitted.
